11 December 2020
17:30	Northampton	v	Bordeaux

12 December 2020
15:15	Bath	v	Scarlets
15:15	Toulon	v	Sale
17:30	Dragons	v	Wasps
17:30	Montpellier	v	Leinster
20:00	Edinburgh	v	La Rochelle

18 December 2020
17:30	Scarlets	v	Toulon
20:00	Wasps	v	Montpellier

19 December 2020
13:00	Leinster	v	Northampton
15:15	La Rochelle	v	Bath
20:00	Bordeaux	v	Dragons
20:00	Sale	v	Edinburgh

15 January 2021
17:30	Northampton	v	Leinster
20:00	Toulon	v	Scarlets

16 January 2021
17:00	Edinburgh	v	Sale
20:00	Montpellier	v	Wasps

17 January 2021
13:00	Bath	v	La Rochelle
15:15	Dragons	v	Bordeaux

22 January 2021
17:30	Leinster	v	Montpellier
20:00	Sale	v	Toulon

23 January 2021
13:00	Bordeaux	v	Northampton
13:00	Scarlets	v	Bath
17:30	La Rochelle	v	Edinburgh
20:00	Wasps	v	Dragons